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Every season, there are new and incredible characters in each series that can captivate and even make viewers fall in love with them. However, the main characters have a special place, especially in anime. Girls are full of energy and have great personalities that steal the spotlight. Although choosing the prettiest ones is difficult, we believe these are the best anime waifus of Winter 2025. Of course, we only considered new anime or girls who did not appear in previous seasons.
5. Natsuko – Zenshu

Maybe in the beginning, Natsuko doesn’t look like waifu material at all and even seems quite unbearable fighting with almost all the Nine Soldiers since the start. However, as the chapters go by, Natsuko shows a more human part of herself, leaving to the side of her addiction to work and having everything under control. That’s when you realize that underneath that oversized hoodie and all that tangle of hair, Natsuko has a big heart; she’s funny and has a beautiful face. She’s probably one of the best animators and directors in anime history.
4. Yui – I Have a Crush at Work

Having a romantic relationship is complicated enough, not to mention that imagine having a partner who works in the same company as you. Yet, Yui stays professional, shares her concerns or goals, and maintains a work-life balance. All this without losing sight of her boyfriend’s needs or problems. Yui is also the ideal girlfriend to keep you motivated and to accept challenges in any aspect of your life. Also, if you are a fan of sweets and chocolates, this girl can give you as many as you want.
3. Meme – The 100 Girlfriends Who Really, Really, Really, Really, Really Love You

We have to admit that this anime has many beautiful waifus to choose from. Just in its second season, which premiered this winter 2025, this anime got five more waifus. Still, what makes Meme in this top is that even though she has a great personality, she is a shy, adorable girl and knows how to replicate the substitute jutsu perfectly. Also, every time Meme disappears, she leaves a cute stuffed animal she made with her hands.
2. Alina – I May Be a Guild Receptionist, but I’ll Solo Any Boss to Clock Out on Time

If you want a much bolder girlfriend, Alina is ideal for the job, as long as she does not have to work overtime. Alina is as cute as she is dangerous, but the repercussions can be unimaginable when she gets in a bad mood. Although this seemingly “sweet and cuddly” receptionist has the power to defeat any threat. The good news is that the best way to calm this waifu down is to help her fill out forms or buy her the best dessert in town.
1. Ulmandra – Headhunted to Another World: From Salaryman to Big Four!

Ulmandra is another waifu with too much personality, as she has superhuman strength, a combative spirit, and a stubborn character. However, this demon warrior is in first place in the best anime waifus of Winter 2025 because she also has a soft spot. Ulmandra was softening the more she got involved with Uchimura, opening herself to the possibility of understanding his culture and learning new ways of doing business with other factions. However, in addition to Ulmandra’s concern for her beloved, she is easily a victim of misunderstandings that she creates. This leads her to be a great comic relief, but without affecting her great demonic ego.